Research progress on water-soluble chitosan
Chitosan has good film-forming property, adsorption, biocompatibility, biodegradability and antimicrobial properties, but it can only be dissolved in weak acidic aqueous solution and cannot be directly dissolved in water, which greatly limits its application. In order to increase its solubility in water, chitosan is modified, the research on the water-soluble derivatives of chitosan is reviewed in this paper, and its application in the protection of paper relics is briefly introduced.
Chitin is a kind of natural polysaccharide macromolecular polymer synthesized by biology in animals and plants, which mainly comes from shrimp shelsl, crab shells, insect shells and so on. Chitosan (CS) is obtained by deacetylation of chitin. The chitin is deacetylated under homogeneous conditions, and water-soluble product can be obtained by controlling the degree of deacetylation at about 50% . The primary hydroxyl group, secondary hydroxyl group and amino group on the glucosamine unit in the chitosan molecular chain, with strong reactivity, which can be modified and embellished by functionalization to improve its solubility.
Sun D F,Zhu C L, Zhang W M, et al.Study on the preparation of water-soluble chitosan by N-acetylation[J]. Chinese Wild Plant Resources,2010, 29(06): 48-50+56.
WangC, Xin M H, Li M C, et al. Synthesis and Antibacterial Activity of O-hexanoylated Chitosan Quaternary Ammonium Salt [J]. Functional Material, 2013, 44(15): 2148-2151.
Zheng G S, Zheng H Z, Xie H G, et al. Preparation of a water-soluble chitosan and its application in microencapsulated cell culture [J], 2015, 46(20): 20078-20082.
Chen H J, Jiang X, Jiang F R, et al. Preparation and pH response of water-soluble butanedioic anhydrid acylated chitosan [J]. Chemical and Biological Engineering, 2015, 32(06): 50-53.
Cui W H, Guo Q, Li Q P, et al. Comparison of structural and functional properties of chitosan and Chitosan-Citric Acid Complex [J]. Food Science, 2017, 38(05): 134-141.
Sashiwa H, Yamamori N, Ichinose Y, et al.Chemical modification of Chitosan, 17 michael reaction of chitosan with acrylic acid in water [J]. MacromoleculeBioscience, 2003(3):231-233.
Sashiwa H, Yamamori N, Ichinose Y, et al.Michael Reaction of Chitosanwith Various Acryl Reagents in Water[J]. Biomacromolecules,2003(6):1250-1254.
Wang H D, Wang J T. Preparation of Chitosan Derivative by SchiffBase and its Antibacterial Activity [J]. Journal of Chemical Engineering of Chinese Universities, 2012, 26(06): 1048-1053.
Lim S H, Hudson S M.Synthesis and antimicrobial activity of a water-soluble chitosan derivative with a fiber-reactive group[J]. CarbohydrateResearch,2004, 339(2):313-319.
Song Y P, Chen X X, Zhang H D. The Modification of Chitosan and Preparation of Nanoparticles [J]. Journal of Shijiazhuang University, 2017, 19(06): 9-14.
Yang L Q, Li R C, Liang S P. Preparation and Antioxidant ActiVity of NoVel Double Quaternary Ammonium Salt DeriVative of Chitosan [J]. Chinese Journal of Applied Chemistry, 2015, 32(03): 322-326.
Xie C F. Study on the synthesis of N- long alkyl chitosan quaternary ammonium salt [J]. Shandong chemical industry, 2016, 45(04): 23-24.
Yu P P, Xia W S. Study on synthesis and antibacterial property of benzoylation chitosan [J]. Food and Machinery, 2011, 27(5): 115-119.
Wang X Q, Zhang Y, Yu Z M. Study on the preparation of N,O- carboxymethyl chitosan antibacterial dye [J]. Journal of Beijing Forestry University, 2016, 38(11):104-110.
Wang T, Cai Z S, Zhang T T, et al. Synthesis of water-soluble N,O-hydroxyethyl chitosan and optimization of its synthetic condition [J]. Chemical Research and Application, 2018, 30(03): 395-399.
Luo Q Q, Li K J, Liu G Y, et al. Preparation and characterization of polyethylene glycol modified chitosan as antibacterial coating for leather [J]. Leather Science and Engineering, 2016, 26(01): 28-32.
Tao F. Synthesis of water-soluble PEI chitosan [J]. China New Technologies and Products, 2016(09): 48-49.
Sun Z M, Chen Q C, Huang J Y, et al. Preparation, characterization and antioxidant activity in vitro of pyridine chitosan [J]. Journal of Nuclear Agricultural Sciences, 2016, 30(02): 295-303.
Yao B T, Chen J W. Preparation of water-soluble chitosan by hydrogen peroxide oxidation degradation [J]. Paper Science & Technology, 2015, 34(06): 60-62+97.
Shen W T. Preparation and Characterization of Water-Soluble Chito-Oligosaccharides [J]. Chemical Industry Times, 2017, 31(04): 18-21.
Huang H B, Zeng G S, Chen Y, et al. Preparation and Characterization of Water-Soluble Chitooligosaccharides Produced by a Facile Method [J]. Packaging Journal, 2018, 10(02): 1-7+50.
Wang X M, Qi Y P, et al. Modified natural polymer materials for paper protection [J]. To Chemistry Journal, 2018(01): 82-87.
Sun Z Q, Qiu J H, Xu F Y, et al. Study on the Conservation of Paper Relic by O-(Hydroxyl Isopropyl)Chitosan [J]. Chemistry&Bioengineering, 2005(01): 39-41.
Cao Y H, Qiu J H, Zhu Z Z, et al. Study on the Conservation ofPaper Based Historic Relics by Cellulose-chitosan Graft Product [J]. China Pup&Paper, 2008(03): 32-35.
Duan D C. Application of bacterial cellulose and chitosan in repairing and strengthening of paper relics and mildew resistance [D]. Liaoning University, 2017.
Copyright (c) 2018 To Chemistry Journal
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.