Secondary Metabolites and Bioactivities of Melastoma Malabathricum (L.) Smith: An Anti-Diarrheal Plant of Bangladesh

  • Minhajur Rahman University of Chittagong
  • Nayema Ferdous University of Chittagong
  • ANM Alamgir University of Chittagong
Keywords: Antibacterial, cytotoxic, ethno-medicinal practice, secondary metabolites

Abstract

Melastoma malabathricum (L.) Smith; a naturally growing plant of Bangladesh is investigated in the present experiment for its secondary metabolites, cytotoxic and antibacterial activities. Among the secondary metabolites alkaloid, flavonoid, sterol, tannin and glycoside found to be present while saponin is absent in its leaf. Ethanolic extract of M. malabathricum leaf showed significant cytotoxicity with the LC50 value of 19.38μg/ml.  In the antibacterial screening, the highest zone of inhibition record was 8 mm (at 100mg/ml) and the lowest was 5 mm (at 50mg/ml). These significant cytotoxic and antibacterial activities also corroborate its ethno-medicinal practices.

 

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Author Biographies

Nayema Ferdous, University of Chittagong

Department of Botany, University of Chittagong, Chittagong-4331, Bangladesh

ANM Alamgir, University of Chittagong

Department of Botany, University of Chittagong, Chittagong-4331, Bangladesh

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Published
2018-12-30
How to Cite
Rahman, M., Ferdous, N., & Alamgir, A. (2018). Secondary Metabolites and Bioactivities of Melastoma Malabathricum (L.) Smith: An Anti-Diarrheal Plant of Bangladesh. To Chemistry Journal, 1(3), 256-262. Retrieved from http://purkh.com/index.php/tochem/article/view/158
Section
Research Articles