Speciation of Cobalt(II) complexes with succinic acid and L-glutamine in Tetra Butyl Ammonium Bromide – water mixtures

Authors

  • Lakshmi Kishore Pilli Andhra University
  • Ramakrishna A M.R.P.G.College, Vizianagaram

Keywords:

Complex Equilibria, Speciation, L-Glutamine, Succinic Acid, Cobalt, Tbab, Miniquad 75

Abstract

Speciation of cobalt(II) complexes with L-glutamine (Gln) and succinic acid (Suc) in varying concentrations (0.0-3.0%, w/v) of TBAB-water mixtures with pH-meter   has been made at an ionic strength of 0.16 mol dm-3 and temperature 303 K using a Control Dynamics-APX 175E/C pH meter. Various models for the species of these ligards are refined by using the computer programs SCPHD and MINIQUAD75.  The active forms of the Cobalt(II) are ML, ML2 and MLH for succinic acid and ML and ML2H for L-glutamine. The trend in the variation of protonation constants with dielectric constant is explained on the basis of electrostatic and non-electrostatic forces. The species distribution with pH at different solvent composition and the plausible equilibria for the formation of the species are also presented.

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Author Biographies

Lakshmi Kishore Pilli, Andhra University

Associate Professor, Department of chemistry, M.R.P.G.College, Vizianagaram

Ramakrishna A, M.R.P.G.College, Vizianagaram

Associate Professor, Department of chemistry, 

References

1] Morin Y; Tětu A; Mercier G (1969). "Quebec beer-drinkers' cardiomyopathy: Clinical and hemodynamic aspects". Annals of the New York Academy of Sciences., 156 (1), 566–576.
2] Nageswara Rao, G. and Ronald S.B. (2002) Effect of solvent on protonation equilibria of L-glutamine and succinic acid. J. Indian Chem. Soc., 79, 416-419.
3] Newsholme EA. (1996) The possible role of glutamine in some cells of the immune system and the possible consequence for the whole animal.Experientia 52(5),455-459.
4] Adjei AA, Matsumoto Y, Oku T, Hiroi Y, Yamamoto S. (1994) Dietary arginine and glutamine combination improves survival in septic mice. Nutr Res. 14, 1591–1599.
5] W K Chang, K D Yang, and M F Shaio (1999) Lymphocyte proliferation modulated by glutamine: involved in the endogenous redox reaction. Journal of Clinical and Experiental Immunology. 117(3), 482–488
6] Guillermo Arango Duque and Albert Descoteaux (2014) Macrophage Cytokines: Involvement in Immunity and Infectious Diseases, Frontiers in Immunology, 5, 491.
7] Edwards RA, Whittaker MM, Whittaker JW, Baker EN, Jameson GB. (2001) Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase. Biochemistry. 40(1), 15-27.
8] Nageswara Rao, G. and Murthy, V.L.S.N. (2004) Effect of dielectric constant of medium on protonation equilibnria of L-glutamine and succinic acid. J. Indian Chem.Soc., 81, 424-426.
9] Pomytkin, I.A., Kolesova, O.E. & Ukhanova, T.J. (2000) PCT Int. Appl. Wo. 28, 944.
10] Chouchani, ET; Pell, VR; Gaude, E; Aksentijević, D; Sundier, SY; Robb, EL; Logan, A; Nadtochiy, SM; Ord, EN; Smith, AC; Eyassu, F; Shirley, R; Hu, CH; Dare, AJ; James, AM; Rogatti, S; Hartley, RC; Eaton, S; Costa, AS; Brookes, PS; Davidson, SM; Duchen, MR; Saeb-Parsy, K; Shattock, MJ; Robinson, AJ; Work, LM; Frezza, C; Krieg, T; Murphy, MP (2014) "Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS". Nature, 515 (7527), 431.
11] Veronique Attali, Marcela Parnes, Yafa Ariav, Erol Cerasi, Nurit Kaiser, Gil Leibowitz (2006) Regulation of Insulin Secretion and Proinsulin Biosynthesis by Succinate, Endocrinology, 147(11), 5110–5118.
12] Henry J. Ledon (1988) Diazo transfer by means of phase-transfer catalysis: di-tert-butyl diazomalonate. Organic Syntheses. Collective Volume, 6, 414.
13] Adhikamsetty, R.K. and Gollapalli, N.R. (2007) Effect of urea on Cobalt(II) complexes of L-glutamine and succinic acid. J. Chemical speciation and bioavailability, 19(3), 105-110.
14] Gran, G. (1988) Equivalence volumes of potentiometric titrations. Anal. Chim. Acta, 206, 111-123.
15] Rao, R. S., Satyanarayana, A. and Rao, G.N. Unpublished work.1989
16] Sylva, R.N. and Davidson (1979) M.R.J.Chem.Soc. Dalton Trans., 232, 465.
17] Padmaja, N., Babu, M.S., Rao, G. N., Rao, R.S. and Ramana, K.V, (1990) Effect of urea on the speciation of 1, 10-phenanthroline complexes of toxic metal ions–computer augmented modeling studies. Polyhedron, 9, 2497-2506.
18] Rao, G. N. and Rao, R.S (1992) A critical examination of computer programs in complex equilibria by pH metry, J. Indian Council Chem, 8, 12-28.
19] Gans, P., Sabatani, A. and Vacca, A. (1976) An improved computer program for the computation of formation constants from potentiometric data. Inorg. Chim. Acta, 18, 237-239.
20] Ramakrishna, A and Prasad, U.S.N. (2019) Protonation of succinic acid and L-glutamine in 0.0 to 3.0% w/v in Tetra Butyl Ammonium Bromide – water mixtures. Chinese journal of chemical society., comunicated
21] Braibanti, A., Rao, R.S., Babu, A.R and Rao, G.N. (1995) CEES, Expert system for complex equilibria, 1. MODGEN-model generator for metal ligand equilibria in solution phase. Ann. Chim. (Italy), 85, 17-29.

Published

2020-04-30

How to Cite

Lakshmi Kishore Pilli, & Ramakrishna A. (2020). Speciation of Cobalt(II) complexes with succinic acid and L-glutamine in Tetra Butyl Ammonium Bromide – water mixtures. To Chemistry Journal, 5, 18-24. Retrieved from http://purkh.com/index.php/tochem/article/view/691

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Section

Research Articles