AN OVERVIEW OF CHIRAL DRUGS
Abstract
We describe a one-pot 4 aspect synthesis of pyrano[2,3-c]pyrazoles from hydrazine hydrate or phenyl hydrazine, ethyl acetoacetate, an aldehyde, and malononitrile withinside the presence of catalytic quantities of a caffeine as a inexperienced catalyst in water at 50 ºC. The gift protocol gives the benefits of a easy response, a short response time, a excessive product yield, and an environmentally-friendly, easilypurified, and economically-available catalyst.
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